[OHBM 2024] Human Cerebral Cortex Organization Estimated by Functional PET-FDG Metabolic Connectivity
Functional connectivity (FC) derived from BOLD-fMRI has provided significant insights into human brain organization. The recent introduction of constant-infusion functional [18F]PET (fPET)-FDG has enabled us to track dynamic changes in glucose metabolism over time, sparking growing interest in ‘metabolic connectivity’ (MC)—the temporal synchrony of FDG-based metabolic dynamics between distant brain regions. In this study, we employed a connectivity gradient-based analysis scheme on a resting-state simultaneous fPET-fMRI dataset, aiming to characterize the detailed cortical organization of fPET-derived MC and understand its differences from fMRI-derived network structuresAbstract presented at OHBM 2024, currently working on manuscript.
